K. Madlool, A., N. A. Jafar, N., N. M. Al-Sharify, A. (2014). Synthesis of N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide and Spectrofluorometric Study. Alustath, 0(56), 394-404.
Ammar K. Madlool; Nadhir N. A. Jafar; Abbas N. M. Al-Sharify. "Synthesis of N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide and Spectrofluorometric Study". Alustath, 0, 56, 2014, 394-404.
K. Madlool, A., N. A. Jafar, N., N. M. Al-Sharify, A. (2014). 'Synthesis of N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide and Spectrofluorometric Study', Alustath, 0(56), pp. 394-404.
K. Madlool, A., N. A. Jafar, N., N. M. Al-Sharify, A. Synthesis of N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide and Spectrofluorometric Study. Alustath, 2014; 0(56): 394-404.

Synthesis of N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide and Spectrofluorometric Study

Iraqi National Journal Of Chemistry
Article 1, Volume 0, Issue 56, December 2014, Pages 394-404
Authors
Ammar K. Madlool; Nadhir N. A. Jafar; Abbas N. M. Al-Sharify
Abstract
Abstract
N-(4-Chlorophenyl)-2-methoxy-4-methylbenzamide (3) is synthesized from reacting carboxylic acid (1) with 4-chloroaniline (2) by using N,N’-dicyclohexylcarbodiimide (DCC) and 1-hydroxybezotriazole (HOBt) as coupling reagent. The product is confirmed by IR, 1H-NMR and elemental analysis . The conditions of fluorescence behaviours are studied such as solvent, pH, temperature, time, concentration effect and binding constant at λex340 nm and λem 380 nm. The best fluorescence intensity is obtained at pH = 5 and temperature 25 0C, while the fluorescence intensity remains stable with increasing of time. The LOD, LOQ, S.D and R.S.D% of compound 3 are found 0.2691 mg.L-1, 0.898 mg.L-1, 0.591 and 1.369 respectively.
Keywords
DCC; coupling reagent; fluorescence intensity; pH and binding constant
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